Fragmentation of Dicarboxylic and Tricarboxylic Acids in the Krebs Cycle Using GC-EI-MS and GC-EI-MS/MS

Analysis of Underivatized Steroids Using Cold EI GC/MS

Analysis of organic acids of tricarboxylic acid cycle in plants using GC-MS, and system modeling

Background: Leaves of 15 plant species were collected from the catchment areas of the river Beas, Punjab, India, and analyzed for organic acids of tricarboxylic acid cycle, viz., citric acid (CA), succinic acid (SA), fumaric acid (FmA), and malic acid (MA). Methods: Gas chromatography-mass spectrometry (GC-MS) was used to determine the content of organic acids in the leaves of plant species. Tw...

Determination of strychnine in human blood using solid-phase extraction and GC-EI-MS.

A rapid, simple, and sensitive method has been developed for the identification and quantitation of strychnine in human blood. The sample cleanup procedure involved solid-phase extraction with Oasis(R) HLB cartridges. The extracts were analyzed by gas chromatography-electron impact ionization-mass spectrometry. Limits of detection (LOD) and quantitation (LOQ) were 0.03 and 0.10 microg/mL, respe...

Determination of furosemide in whole blood using SPE and GC-EI-MS.

A simple and rapid method was validated to determine furosemide in whole blood. The experimental work was performed so that all validation parameters are considered simultaneously in a one-day assay protocol. A solid-phase extraction procedure using BondElut-LRC Certify columns was used to extract this compound from blood samples, while ketoprofen was used as an internal standard. The extracts ...

Identification of nematicidal fatty acids and triglycerides from seeds of Jubaea chilensis by GC-EI-MS and chemical transformation methods.

Nematicidal bioassay-guided fractionation of the n-hexane extract of the seeds of Jubaea chilensis led to the identification of eight known fatty acids and a mixture of triglycerides, reported for the first time for this species. In addition, their corresponding methyl esters were identified to be artifacts generated during the extraction and isolation procedures by using GC-EI-MS and chemical ...